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Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans

机译：秀丽隐杆线虫的核苷酸切除修复能力下降

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摘要

Repair of UVC-induced DNA damage in Caenorhabditis elegans is similar kinetically and genetically to repair in humans, and it slows significantly in aging C. elegans.

机译：在秀丽隐杆线虫中，UVC诱导的DNA损伤的修复在动力学和遗传上与人类修复相似，并且在衰老的秀丽隐杆线虫中显着减慢。

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Meyer, Joel N; Boyd, Windy A; Azzam, Gregory A; Haugen, Astrid C; Freedman, Jonathan H; Van Houten, Bennett;
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年度 2007
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正文语种 {"code":"en","name":"English","id":9}
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专利

1. Nucleotide excision repair genes are expressed at low levels and are not detectably inducible in Caenorhabditis elegans somatic tissues, but their function is required for normal adult life after UVC exposure. [J] . Boyd WA, Crocker TL, Rodriguez A Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 2010,第1a2期

机译：核苷酸切除修复基因在秀丽隐杆线虫体细胞组织中低水平表达且不可检测地诱导，但是其功能是紫外线暴露后正常成年生活所必需的。
2. Nucleotide excision repair and the degradation of RNA pol II by the Caenorhabditis elegans XPA and Rsp5 orthologues, RAD-3 and WWP-1. [J] . Astin JW, ONeil NJ, Kuwabara PE DNA repair . 2008,第2期

机译：秀丽隐杆线虫XPA和Rsp5直向同源物RAD-3和WWP-1的核苷酸切除修复和RNA pol II的降解。
3. The nucleotide excision repair pathway is required for UV-C-induced apoptosis in Caenorhabditis elegans. [J] . Stergiou L, Doukoumetzidis K, Sendoel A, Cell death and differentiation . 2007,第6期

机译：紫外线切除诱导秀丽隐杆线虫的细胞凋亡需要核苷酸切除修复途径。
4. Polymorphisms of Genes Related to Nucleotide Excision Repair and Cell Cycle Pathways, Arsenic Exposure, and Bladder Cancer [C] . Ya-Yun Cheng, How-Ran Guo Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：与核苷酸切除修复和细胞周期途径，砷暴露和膀胱癌相关的基因的多态性
5. Effects of base sequence on the removal of DNA damage by nucleotide excision repair mechanisms in vitro. [D] . Liu, Yang. 2010

机译：碱基序列对体外核苷酸切除修复机制去除DNA损伤的影响。
6. Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans [O] . Joel N Meyer, Windy A Boyd, Gregory A Azzam, 2007

机译：秀丽隐杆线虫的核苷酸切除修复能力下降
7. Decline of nucleotide excision repair capacity in aging [O] . 2007

机译：衰老中核苷酸切除修复能力的下降

Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans

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